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Oct 18 / 2016

Generic Modafinil Off-Label uses

Generic Modafinil Off-Label Uses Generic Modafinil Off-Label Uses

Modafinil is known to be a stimulant of the central nervous system. It was approved in 1998 by FDA. Since that time it has become a new class of the most effective wakefulness promoting medications. In comparison with traditional stimulants, this one won’t produce a lot of jitteriness, fatigue or any anxiety. It’s initially was approved for treating narcolepsy and other similar sleep problems.

Except this, the effectiveness of the medication was shown in the treatment of cancer-related fatigue, multiple sclerosis and even Parkinson’s disease. Many people, who suffer from chronic fatigue, may often experience such symptoms as lack of attention and poor concentration. In this case they are prescribed Generic Modafinil. At the same time many people with chronic fatigue can be also affected with excessive daytime sleepiness and even OSA.  

The medication is often used in the treatment of fatigue and sedation in a number of health conditions, such as Parkinson’s disease, depression, chronic fatigue syndrome, spastic cerebral palsy.  The medication is experimentally used for treating atypical depression, which is characterized by over-eating, hypersomnia, rejection-sensitivity and low levels of energy. In fact, this health problem is quite common these days. The results of these studies are quite promising, but still they need some large-scale researches.

Military & Astronauts

It’s known that militaries from particular countries are extremely interested in Modafinil. They use it as amphetamine alternative and can easily order Modafinil online.  They have been using these drugs in situations, where the militaries faced sleep deprivation, for example, during long missions. French government allowed the Foreign Legion using the medication in certain operations. The United Kingdom has spent almost £300,000 on Modafinil investigation.

The Indian Air Force has also announced about including Modafinil into their contingency plans (2011). In US military, the medicine was approved to be used in certain missions of Air Force. Simultaneously, they are investigating other uses of the drug. In 2012 they announced Modafinil to be the only medication approved, able managing fatigue syndrome. Dextroamphetamine is not used by the military anymore. According to one Canadian Journal, Modafinil is often used by many astronauts during long-term missions while on the International Space Station.

It is available to the space crew   for optimizing their performance and struggling with fatigue. Officially Modafinil is approved by FDA for treating sleep apnea, narcolepsy and SWSD. In spite of this, many physicians indicate Modafinil for treating many other health conditions. Of course, an off-label use is not well-studied. FDA doesn’t allow advertising drugs for uses, they haven’t yet approved.

As for manufacturers, they have a right to advertise their medications for what they are labeled for. At the same time they have an indirect way of promoting off-label usages of their medication. These often come from the practice by the community. Doctors and many nurses may also figure them out while communicating with their patients.

Off-label uses of Modafinil include:
- memory decline, connected with age
- attention deficit disorder
- fatigue, which is the cause of very intensive work, which lasts for hours
- fatigue, which is the cause of chemotherapy
- fatigue caused by multiple sclerosis
- fatigue in people, who should be awake for a long time, such as doctors, soldiers, astronauts or students
- Alzheimer’s disease problems -Parkinson’s disease -cocaine addiction patients
- sleepiness, which was caused by some other medications

Currently, there are so many studies, which are investigating additional uses of Modafinil, except that for narcolepsy, OSA and SWSD. 

Is It Safe To Use?

Modafinil was approved by FDA in 1998. It has some side effects, which are not tolerated by everyone, but still, generally, considered quite safe. According to one study, conducted at the Harvard Medical School and University of Oxford, the risks of the medication were small. The research also showed that Modafinil is able improving cognitive performance, including decision making and even planning.

Modafinil vs Other Stimulants

The structure of Modafinil is quite different, in comparison with other stimulants. Its mechanism of action is not fully understood, but it’s completely different from other dopaminergic stimulant medications. Moreover, it doesn’t have so many withdrawal effects and if there are any, they are not severe.  The medication belongs to Schedule IV drugs in the USA.

Who Can Use It?

The medication is approved only for adults and children, who are over 16 years. Only those, who are suffering from sleep disorders, should take it.  Modafinil vs Caffeine In comparison with caffeine, which affects the whole nervous central system and leads to insomnia, jitteriness and long sleep bouts, Modafinil just influences area of the brain, which is responsible for sleep and wake cycles. When the effects of the medication wear off, the sleep patterns of a person would return as well. Many clinical studies have shown that Modafinil is less likely causing nervousness and other similar symptoms.

Mood Enhancer

When you buy Modafinil online, you should know about all its additional uses. The medication is also called a mood-brightening and memory-improving psychostimulants. It’s not only enhances the feeling of wakefulness, but improves memory, cognitive performance and even vigilance. It won’t cause you excessive locomotor activity, in comparison with other stimulants, including coffee and cocaine.

In fact, the medication possesses cleaner and smoother effects, compared to other amphetamines. The elimination life of the medication in adults is from 12 to 15 hours. According to the current studies, Modafinil is considered quite a safe drug, which is also effective and quite well-tolerated by the majority of people.


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